Since then, 16 states have passed laws to allow the use of CBD products with a physician's recommendation for treatment of certain medical conditions.Studies show that, essentially, the more full-spectrum CBD you consume, the stronger the effects. Effects still increase as doses rise, but only up to a certain threshold. After that point, it doesn’t matter how much CBD isolate you consume; you won’t notice the difference. CBD isolate, on the other hand, focuses exclusively on cannabidiol. Well, it isn’t until you increase the dose of full-spectrum CBD that its efficacy becomes apparent.